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PILOT D60 MAGNETIC MIXER ASSEMBLIES

The go-to solution for pilot-scale applications (till 1000 L working volumes). The D60 series magnetic mixers throughout the years gained increased interest for their unique ability of providing high mass transfer rates in pilot-scale vessels, which raises them above other alternatives. In the proposed design, a gap between the outer rotors and the hermetic containment housing is maintained in order to avoid grinding between rotating and static elements. Simultaneously, two concentric lines of suction slots were machined into the body of the outer rotor. The upper layer slots guide the liquid in such a way, so that the movement on the boundary layer during rotation would be directed towards the gap between the containment housing and outer rotor. In the vicinity of the lower suction slot layer the flow direction is opposite that of the upper layer, so that liquid would move from the air gap to the outside environment.
Such design aspects, considering the suction slots, were envisioned, in order to avoid flow stagnation in the air gap between the outer rotor and the containment housing, which is crucial during both microorganism cultivation/fermentation processes and CIP procedures.

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Bioreactor tor Laboratory

Peltier based system

EDF-1.2 

EDF 1.2 Bioreactor with peltier control

MAGNETIC MIXERS

SIMENS SIMATIC S7-1500

USER-FRIENDLY, EFFICIENT

PELTIER BASED SYSTEM

CLEANABLE, STERILE LID

Novel magnetic drive improves the sterility and ensures intensive mixing  conditions

based control and 15” operator panel create  high standard of process supervision and more

Advanced Operator Panel: Marking, Actions, Recipe Management, and Enhanced Functionality

No water and drain connections required, simplifying the installation

No welded components in the lid create ideal cleaning and sterility conditions

Features and benefits
Novel magnetic drive improves the sterility and ensures intensive mixing  conditions

Siemens Simatic S7-1500 based control and 15” operator panel create  high standard of process supervision , ensures remote service of software, and hardware service from local Siemens representative

User friendly operator panel with many functional

possibilities such as

  • Marking of sampling and induction time and volume

  • Operator action journal

  • Creating, selecting, saving and editing of recipes.  

 

Peltier systems:
No water and drain required

No welded components in the lid create ideal cleaning and sterility conditions

Convenient design with collapsible condenser to decrease the height of vessel during autoclaving

Operator Panel Screenshots
Advanced Operator Panel: Marking, Actions, Recipe Management, and Enhanced Functionality
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EDF-1.2 Bioreactor

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Microbiology

EDF-1.2

Peltier controlled system

The EDF-1.2 is an innovative twin bioreactor, designed for both research and process development in fermentation and cell culture.

Peltier element cooled condensers provide exceptional exhaust gas cooling without the use of circulation water. The robust construction and fan-driven heat exchange develop enough power to cool and condense even high-temperature processes.

Vessel

Total volume (L)   0.9

Working volume (L)   0.4-0.7

Vessel type   Borosilicate glass

Diameter/ Height (mm)   85/165

Aeration

Control   Rotameter, TMFC (option)

Gas supply   Air, + O2 (option)

Flow range, L/min   0.5 - 10

Sparger   MIcrosparger 5-14 um

Filters   D51 mm 0.2 μm PTFE

Exhaust gas condensor   Peltier

Mixing

Drive  Top magnetically coupled aseptic mixer

Rotation speed range (rpm)  40 - 1800 (2000 with sparging)

Mixer   2 Rushton turbines

Control

Controller   Siemens Simatic S7 - 1500

Operator panel   Touch screen BeeTronics, 15TS7 15’’ LED

Temperature   Peltier heating/cooling Control limits: 10 °C - 50 °C Measurement accuracy +/- 0.1 °C and control accuracy +/- 0.2 °C

pH   Hamilton (different options, including Arc).
Acid/ Base
2 - 12 +/- 0,01pH units

pO2   Hamilton or Mettler Toledo sensors (different options, including Arc).
Control: mixing + О2 (option).
0 - 150 % +/- 1%

Foam   Conductivity sensor

Feeding   0.01-20 ml/min according to the set profile

Peristaltic pumps   3 built-in variable speed pumps. Additional external 4-20 mA controlled pumps (optional)

Dimensions

Total (mm)  540(W) х 350(H) х 410(D)

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