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BioPC fermentation control and design software


The complications of fed-batch process control are solved thanks to the state-of-the art model
predictive control (MPC) node. Thus, BioPC provides unique options for designing, control and optimization of fed-batch bioprocesses.

The suite includes:

  • Over 50 built-in bioprocess blueprints for the most popular cell lines, which can be used as a starting point for any project;

  • Cultivation medium composition optimization plug-in;

  • Soft-sensor development plug-in;

  • DoE plug-in;

  • Statistical analysis tools;

  • Bioprocess construction nodes (control element nodes, mathematical nodes, logical operator nodes and many more), which allow to create custom control loops;

  • MPC tool for fed-batch process design and optimization;

BioPC is cross-platform and runs equally well on Linux, Windows, and Macintosh computers. Its
interface is node-based to provide intuitive and easy-to-learn workflow.
The BioPC software ships alongside the communication module (COMbox), which can be factory configured to the users demand: up to 10 different control elements and up to 10 sensor inputs*.

Sensing and control equipment can be configured and shipped alongside the software.
*Sensor inputs and control element outputs can be configured on-demand.

You can send your order inquiry to:

BioPC is a all-in-one node-based bioprocess development software suit. It supports the entirety of the traditional fermentation technology pipeline, e.g. design of experiments (DoE), control of fermentations/cultivations, data gathering and statistical analysis, even process modelling and optimization.


Advanced users are given the necessary tools to create custom fermentation control loops, develop soft-sensors for hard-to-measure metabolites, fine-tune process models and use them to increasing the efficiency of any application.

BioPC is well suited to small, medium and large manufacturers, which are looking for ways of increasing their product yields.


Furthermore, BioPC is a powerful tool for scientific groups, which are working on the verge of biotechnology and are looking for sophisticated solutions for otherwise complicated tasks.
Examples of BioPC applications have shown to:

  • Improve E. coli fed-batch cultivations biomass production by 25%.

  • Improve P. pastoris fed-batch cultivations biomass production by 30%.

  • Improve E. coli fed-batch fermentation recombinant protein production by 15%.

  • Improve S. cerevisiae fed-batch cultivations biomass production by 20%.



This application is designed to calculate the feeding profile for a given specific biomass growth rate or target substrate concentration in the cultivation medium, taking into account the effect of the substrate and biomass concentrations. Additionally, the application is able to estimate the cultivation process model parameters based on the experimental data To launch the program open fed-batch-calculation>fed-batch-calculation.exe and follow the instructions in program

Program is intended for Windows(32 and 64 bit) operating systems

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